I. The Cell
1. The Cell in Health and Illness
2. Cellular Injury, Adaptations, and Maladaptive Changes
3. Genetic Basis of Disease
II. Integrated Body Processes
4. Stress, Exercise, and Immobility
5. Obesity and Nutritional Imbalances
6. Pain
III. Fluid, Electrolyte, and Acid-Base Homeostasis
7. Fluid and Electrolyte Imbalances
8. Acid-Base Imbalances
IV. Infection and Inflammation
9. Inflammation and Dysfunctional Wound Healing
10. Infectious Diseases
11. Disorders of the Immune System
V. Hematologic Disorders
12. Disorders of White Blood Cells
13. Disorders of Red Blood Cells
14. Disorders of Platelets, Hemostasis, and Coagulation
VI. Disorders of Cardiovascular Function
15. Arterial Disorders
16. Ischemic Heart Disease and Conduction Disorders
17. Heart Failure
18. Valvular Heart Disease
19. Disorders of the Venous System
VII. Pulmonary Disorders
20. Respiratory Inflammation and Infection
21. Restrictive and Obstructive Pulmonary Disorders
VIII. Renal and Urological Disorders
22. Renal Disorders
23. Urological Disorders
IX. Hormonal and Reproductive Disorders
24. Endocrine Disorders
25. Diabetes Mellitus and the Metabolic Syndrome
26. Disorders of the Female Reproductive System
27. Disorders of the Male Reproductive System
28. Sexually Transmitted Diseases
X. Gastrointestinal Disorders
29. Disorders of the Esophagus, Stomach, and Small Intestine
30. Common Disorders of the Large Intestine
31. Infection, Inflammation, and Cirrhosis of the Liver
32. Gallbladder, Pancreatic, and Bile Duct Dysfunction
XI. Neurological Disorders
33. Cerebrovascular Disorders
34. Chronic and Degenerative Neurological Disorders
35. Brain and Spinal Cord Injury
36. Psychobiology of Behavioral Disorders
XII. Musculoskeletal Disorders
37. Musculoskeletal Trauma
38. Degenerative Disorders of the Musculoskeletal System
39. Infection and Inflammatory Disorders of the Musculoskeletal System
XIII. Cancer
40. Cancer
XIV. Integumentary Disorders
41. Skin Disorders
42. Burns
XV. Sensory Disorders
43. Eye Disorders
44. Ear Disorders
XVI. Disease Across the Life Span
45. Chapter 45: Pediatric Disorders 1053
46. Chapter 46: Pathological Concepts of Aging 1091
47. Chapter 47: SIRS, Sepsis, Shock, MODS, and Death 1107